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1

Inactivation of the MouseHPRTLocus by a 203-bp Retroposon Insertion and a 55-kb Gene-Targeted Deletion: Establishment of New HPRT-Deficient Mouse Embryonic Stem Cell Lines

Hirohisa Tsuda, Catherine E. Maynard-Currie, Laura H. Reid, Takayuki Yoshida, Koji Edamura, Nobuyo Maeda, Oliver Smithies, Aya Jakobovits

Journal:

Year:

1997

Language:

english

File:

PDF, 1.76 MB

english, 1997

2

From XenoMouse technology to panitumumab, the first fully human antibody product from transgenic mice

Jakobovits, Aya, Amado, Rafael G, Yang, Xiaodong, Roskos, Lorin, Schwab, Gisela

Journal:

Nature Biotechnology

Year:

2007

Language:

english

File:

PDF, 3.68 MB

english, 2007

3

Expression of N-myc in teratocarcinoma stem cells and mouse embryos

Jakobovits, Aya, Schwab, Manfred, Bishop, J. Michael, Martin, Gail R.

Journal:

Year:

1985

File:

PDF, 471 KB

1985

4

Target Antigens for Prostate Cancer Immunotherapy

Douglas C. Saffran, Robert E. Reiter, Aya Jakobovits, Owen N. Witte

Journal:

Cancer and Metastasis Reviews

Year:

1999

Language:

english

File:

PDF, 92 KB

english, 1999

5

Human B lymphocytes form rosettes after insertion of T lymphocyte membrane constituents

Aya Jakobovits, Mireille Rosenberg, Nathan Sharon

Journal:

European Journal of Immunology

Year:

1981

Language:

english

File:

PDF, 376 KB

english, 1981

6

Analysis of Homozygous Mutant Chimeric Mice: Deletion of the Immunoglobulin Heavy-Chain Joining Region Blocks B-Cell Development and Antibody Production

Aya Jakobovits, German J. Vergara, Jacqueline L. Kennedy, Joanna F. Hales, Ryan P. McGuinness, Denise E. Casentini-Borocz, Daniel G. Brenner and Gillis R. Otten

Journal:

Proceedings of the National Academy of Sciences

Year:

1993

Language:

english

File:

PDF, 1.05 MB

english, 1993

7

SPECIFIC LYSIS OF ANTIGENICALLY IRRELEVANT CELLS BY CYTOTOXIC T LYMPHOCYTES UPON INSERTION OF APPROPRIATE ANTIGENS INTO THE TARGET CELL PLASMA MEMBRANES

SCHICK, BARBARA, JAKOBOVITS, AYA, SHARON, NATHAN, BERKE, GIDEON

Journal:

Transplantation Journal

Year:

1983

File:

PDF, 778 KB

1983

8

Germ-line transmission and expression of a human-derived yeast artificial chromosome

Jakobovits, Aya, Moore, Amy L., Green, Larry L., Vergara, German J., Maynard-Currie, Catherine E., Austin, Harry A., Klapholz, Sue

Journal:

Year:

1993

File:

PDF, 609 KB

1993

9

Isolation of human erythrocyte membranes and their outer surface proteins by covalent fractionation on solid support

Yuval Eshdat, Aya Prujansky-Jakobovits

Journal:

Year:

1979

Language:

english

File:

PDF, 941 KB

english, 1979

10

The human immunoglobulin loci introduced into mice: V (D) and J gene segment usage similar to that of adult humans

Michael L. Gallo, Vladimir E. Ivanov, Aya Jakobovits, C. Geoffrey Davis

Journal:

European Journal of Immunology

Year:

2000

Language:

english

File:

PDF, 104 KB

english, 2000

11

Production of fully human antibodies by transgenic mice

Journal:

Current Opinion in Biotechnology

Year:

1995

Language:

english

File:

PDF, 504 KB

english, 1995

12

Production of Antigen-Specific Human Antibodies from Mice Engineered with Human Heavy and Light Chain YACs

AYA JAKOBOVITS, LARRY L. GREEN, MARGARET C. HARDY, CATHERINE E. MAYNARD-CURRIE, HIROHISA TSUDA, DONNA M. LOUIE, MICHAEL J. MENDEZ, HADI ABDERRAHIM, MASATO NOGUCHI, DOUGLAS H. SMITH, YONGJUN ZENG, NATH

Journal:

Annals of the New York Academy of Sciences

Year:

1995

Language:

english

File:

PDF, 549 KB

english, 1995

13

STEAP: A Prostate-Specific Cell-Surface Antigen Highly Expressed in Human Prostate Tumors

Rene S. Hubert, Igor Vivanco, Emily Chen, Shiva Rastegar, Kahan Leong, Steve C. Mitchell, Rashida Madraswala, Yanhong Zhou, James Kuo, Arthur B. Raitano, Aya Jakobovits, Douglas C. Saffran and Daniel

Journal:

Proceedings of the National Academy of Sciences

Year:

1999

Language:

english

File:

PDF, 1.46 MB

english, 1999

14

The long-awaited magic bullets: therapeutic human monoclonal antibodies from transgenic mice

Jakobovits, Aya

Journal:

Expert Opinion on Investigational Drugs

Year:

1998

Language:

english

File:

PDF, 203 KB

english, 1998

15

[Part 2: Biological Sciences] || Alteration of Lymphocyte Surface Properties by Insertion of Foreign Functional Components of Plasma Membrane

Aya Prujansky-Jakobovits, David J. Volsky, Abraham Loyter and Nathan Sharon

Journal:

Proceedings of the National Academy of Sciences

Year:

1980

Language:

english

File:

PDF, 1.70 MB

english, 1980

16

AGS-PSCA: A FULLY HUMAN ANTIBODY TO PSCA FOR THE TREATMENT OF PANCREATIC CANCER

Jakobovits, Aya, Morrison, Kendall, Jia, Xiao-Chi, Shao, Hui, An, Zili, Raitano, Arthur B, Morrison, Karen, Kanner, Steven B, Gudas, Jean M

Journal:

Year:

2005

Language:

english

File:

PDF, 656 KB

english, 2005

17

Production and selection of antigen-specific fully human monoclonal antibodies from mice engineered with human Ig loci

Journal:

Advanced Drug Delivery Reviews

Year:

1998

Language:

english

File:

PDF, 398 KB

english, 1998

18

Tools of the Trade YAC Vectors: Humanizing the mouse genome

Journal:

Current Biology

Year:

1994

Language:

english

File:

PDF, 453 KB

english, 1994

19

Inserted H–2 gene membrane products mediate immune response phenotype of antigen-presenting cell

Jakobovits, Aya, Frenkel, Ayala, Sharon, Nathan, Cohen, Irun R.

Journal:

Year:

1981

File:

PDF, 398 KB

1981

20

Plucking of lectin receptors from erythrocytes: Isolation of cell surface components without the use of detergents

Aya Jakobovits, Yuval Eshdat, Nathan Sharon

Journal:

Biochemical and Biophysical Research Communications

Year:

1981

Language:

english

File:

PDF, 1.50 MB

english, 1981

21

Two Proto-Oncogenes Implicated in Mammary Carcinogenesis, int-1 and int-2, are Independently Regulated during Mouse Development

Aya Jakobovits, Gregory M. Shackleford, Harold E. Varmus and Gail R. Martin

Journal:

Proceedings of the National Academy of Sciences

Year:

1986

Language:

english

File:

PDF, 1.16 MB

english, 1986

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